| Organised by BITS, the Bioinformatics Training and Service facility of the VIB. |
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Goal
- Get to know the data generated from protein structure determination experiments (NMR, XRAY,...) and where to get it
- Display protein structure data and compare structures, through the use of Yasara
- Calculate the effect of mutations on the stability of your protein, through the use of FoldX.
Summary
This training session will provide the basics of protein structure determination and how this information is stored in databases. We will explore and search in online databases containing protein structure information. With the aid of the Yasara View program we will visualize the structure. Different hands-on exercises will allow you to compare the structure of homologues, to predict a structural model of proteins without any structure information and to find homologuous structures.
Training schedule
Schedule
- Lecture
- Exercises
- Exploring the Protein Data Bank
- Visualizing protein structures with YASARA
- Comparing structures
- Predicting the effect of mutations on protein structure
- Predicting protein structure - homology modeling
Trainer
The training is prepared and given by Joost Van Durme of the SWITCH lab.