- Assay development
- High-throughput screening of in-house or custom compound collections
- Automated liquid handling
- Hit optimization
When you are looking for high-throughput screening of large compound collections, then robust screening assays, high-quality screening libraries and advanced robotic systems are the key to success. VIB Compound Screening Facility (CSF) has built up considerable scientific expertise and equipment to complete these tasks with fast and reliable results.
Services CSF has the expertise and equipment to perform a full screening project. This includes:
- Preparation of assay plates
- Compound screening
- Analyzing the effect of the compounds by using microscopes or plate readers
- Advising on assay development
- Services for further compound characterization (EC50, active substructures, initial lead)
Collections Our compound screening collection amounts to a total of 42,000 compounds:
ChemBridge Corporation: - DIVERSet™ (22,000 compounds)
- CNS-Set™ (10,000 compounds)
- NOVACore (10,000 compounds)
Compound storage
To maintain compound integrity during larger periods of time, we use 4titude’s PlateStable™ conditioned storage system.
High-throughput screening equipment
Robotic state-of-the-art high-throughput platform
Visual (microscopy-based) or digital (plate reader-based) read-outs
Contact
CSF Manager
Dominique Audenaert
VIB Compound Screening Facility, UGent (CSF)
UGent-VIB Research Building FSVM
Technologiepark 927
9052 GENT
BELGIUM
phone: +32 9 331 39 36