VIB scientists overview

Structural biology

  • Janine Brunner Lab

     ​​We combine different methods to explore the structure and function of membrane proteins. Our lab focuses in particular on lipid biology and ion channel biophysics​.

  • Nico Callewaert Lab
    • ERC group
    • ​Synthetic biology of the eukaryotic secretory system
    • Novel concepts in biopharmaceuticals
    • Novel technology for discovery of molecular biomarkers of disease
    • Engineering the Mycobacterium-host interface for better vaccines and drugs

  • Lucía Chávez-Gutiérrez Lab
    • ​​​Intramembrane proteolytic mechanism
    • Quantitative enzymology
    • Structure and function of proteases in neurodegeneration

  • Rouslan Efremov Lab
    • ERC group
    • Structure and conformational dynamics of membrane protein complexes by cryo-EM
    • Single particle cryo-EM method development

  • Remy Loris Lab
    • bacterial stress response and Toxin-Antitoxin modules
    • intrinsically disordered proteins
    • macromolecular crystallography and biophysics

  • Joris Messens Lab
    • Study of the proteins and mechanisms that control redox homeostasis
    • Biochemical, structural and quantum chemical expertise in thiol/redox-chemistry

  • Han Remaut Lab
    • ERC group
    • Helicobacter pylori Adhesion - Countering a life-long attachment to the host
    • Chaperone/Usher Pilus Assembly - Towards selective disarmament of adhesive fibers
    • Curli - Structural biology of controlled amyloid deposition

  • Savvas Savvides Lab
    • ​Pro-inflammatory signaling complexes 
    • Extracellular assembly and activation principles of oncogenic receptor tyrosine kinases
    • in vivo protein crystals in immunity, inflammation and cancer
    • structure-guided protein engineering and drug/antagonist design

  • Jan Steyaert Lab
    • chaperone-assisted X-ray crystallography: xaperones
    • RNA modification: structure-function relationship of nucleoside and nucleic acid-modifying enzymes

  • Peter Tompa Lab
    • ​Structural biology of disordered of proteins
    • Structure of “oversized” proteins
    • In-cell NMR of proteins
    • Bioinformatics of protein disorder

  • Shoshana Wodak Lab
    • ​Analysis of structural energetic and dynamic principles governing protein stability and protein interactions
    • Computational and bioinformatic analyses of Protein-protein, protein-DNA and protein-ligand interactions
    • Interaction proteomics: Quantitative and integrative computational approaches for analyzing physical and functional interactions between proteins at the cellular level