VIB scientists overview

Proteomics

  • Rudi Beyaert Lab

    • Protein-protein interactions, phosphorylation and ubiquitination
    • Cytokine, Toll-like receptor and T cell receptor signal transduction
    • NF-kappaB signaling in inflammation and cancer
    • Novel therapeutic targets and tools
  • Nico Callewaert Lab

    • ​Synthetic biology of the eukaryotic secretory system
    • Novel concepts in biopharmaceuticals
    • Novel technology for discovery of molecular biomarkers of disease
    • Engineering the Mycobacterium-host interface for better vaccines and drugs
  • Ive De Smet Lab

    • ​unraveling phosphorylation-related signaling mechanisms associated with cell division and differentiation in plants
  • Sven Eyckerman Lab

    • ​protein complex biology
    • Virotrap: purification of protein complexes using virus-like particles
    • genome engineering to support interactomics
    • multiplex profiling in signal pathways
  • Kris Gevaert Lab

    • Contemporary mass spectrometry-driven proteomics
    • Protein modifications
    • Proteogenomics
  • Matthew Holt Lab

    • Basic mechanisms of signal transduction in astrocytes
    • Mechanisms of neuron-astrocyte interaction
    • Role of astrocytes in neuropathology
  • Proteomics Expertise Center

    • ​Targeted Proteomics - monitoring the metabolic or inflammatory state of the cell
    • Ubiquitin-like modifications - proteomics strategies to map ISGylation sites
    • Antigenic peptides - finding novel epitopes for vaccine development
  • Mohamed Lamkanfi Lab

    • NOD-like receptor and inflammasome signaling networks,​ and their role in human disease
    • proteomics and genomics technologies for pathway discovery
  • Stuart Maudsley Lab

    • Understanding complex and multifactorial neurodegenerative diseases by unraveling interaction networks of genes and proteins.
    • Generation of receptor-based therapeutic strategies to regulate pathological disease networks.
    • Development of novel bioinformatic tools for therapeutic design
  • Jan Tavernier Lab

    • leptin receptors: molecular mechanisms underlying receptor activation upon ligand binding
    • MAPPIT two-hybrid toolbox based on JAK/STAT pathway
    • protein interactions important in the innate immune response
  • Peter Tompa Lab

    • ​Structural biology of disordered of proteins
    • Structure of “oversized” proteins
    • In-cell NMR of proteins
    • Bioinformatics of protein disorder
  • Peter Vandenabeele Lab

    • cell death modalities in vivo
    • in vivo focus on epithelial biology: skin and intestine
    • transgenic mouse models for caspases and RIP kinases