VIB scientists overview

Cardiovascular medicine

  • Gabriele Bergers Lab

    • Functional irregulation of the tumor microenvironment and tumor cell compartment
    • Tumor niches and therapeutic resistance
    • Resistance to antiangiogenic therapy
    • Vascular and immunomodulation in cancer
  • Cédric Blanpain Lab*

    • ​embryonic development
    • stem cells and adult homeostasis
    • stem cells and tumor initiation
    • cancer stem cells
  • Peter Carmeliet Lab

    • ​Vascular metabolism & (lymph)angiogenesis
    • Omics analysis of healthy and diseased human and mouse endothelial/vascular cells to understand and target metabolic pathways
    • Therapeutic anti-angiogenesis: tumor vessel normalization (TVN)
    • Endothelial cell metabolic target discovery and drug development
  • Holger Gerhardt Lab

    • Importance of tip cell biology in vascular patterning, tumour angiogenesis and ischemic disease

     

  • Diether Lambrechts Lab

    • Leverage the genetic and epigenetic annotation of tumors to improve cancer prevention, diagnosis, prognosis and therapy
    • Apply cutting-edge genetic technologies and bioinformatics and integrate genomic data sets with clinical and fundamental biological information
    • To characterize how the tumor microenvironment influences tumor cells and determines response to cancer therapies
  • Massimiliano Mazzone Lab

    • Genetic and molecular mechanisms regulating blood vessel formation
    • Influence of the microenvironment on macrophage phenotypes and positioning in the context of cancer and ischemia
    • Metabolic control of tumor immunity and resistance to immunotherapy
  • Massimo Santoro Lab

    • identify new metabolic pathways important in vascular development, homeostasis and disease
    • study redox signaling and antioxidant response in endothelial cells