VIB scientists overview

Systems biology

  • Stein Aerts Lab

    • ERC group​
    • cellular decision making and genome regulation
    • single-cell transcriptomics and epigenomics
    • systems biology of gene regulation
    • gene regulatory networks in the Drosophila brain and retina
    • high-throughput enhancer assays and computational enhancer models
  • Cédric Blanpain Lab*

    • ​ERC group
    • embryonic development
    • stem cells and adult homeostasis
    • stem cells and tumor initiation
    • cancer stem cells
  • Bruno Cammue Lab*

    • antimicrobial plant peptides including plant defensins
    • novel stress-induced plant peptides
    • plant-fungus interactions and plant disease analysis
    • biocontrol of plant diseases
  • Peter Carmeliet Lab

    • ERC group​
    • Vascular metabolism & (lymph)angiogenesis
    • Omics analysis of healthy and diseased human and mouse endothelial/vascular cells to understand and target metabolic pathways
    • Therapeutic anti-angiogenesis: tumor vessel normalization (TVN)
    • Endothelial cell metabolic target discovery and drug development
  • Ive De Smet Lab

    • ​unraveling phosphorylation-related signaling mechanisms associated with cell division and differentiation in plants
  • Sven Eyckerman Lab

    • ​protein complex biology
    • Virotrap: purification of protein complexes using virus-like particles
    • genome engineering to support interactomics
    • multiplex profiling in signal pathways
  • Sarah-Maria Fendt Lab

    • ​Cancer cells have a distinct metabolism adapted to their proliferative needs
    • Our focus is centered on understanding and targeting the differential metabolism of cancer cells
  • Martin Guilliams Lab

    • ​​ERC group
    • Ontogeny of dendritic cells and macrophages
    • Functional characterization of dendritic cell and macrophage subsets across species and tissues in steady state and inflammation

  • Matthew Holt Lab

    • ERC group
    • Basic mechanisms of signal transduction in astrocytes
    • Mechanisms of neuron-astrocyte interaction
    • Role of astrocytes in neuropathology
  • Dirk Inzé Lab

    • ERC group
    • molecular mechanisms regulating leaf organ size
    • systems biology of drought tolerance
    • computational approaches to elucidate plant growth
  • Diether Lambrechts Lab

    • ERC group
    • Leverage the genetic and epigenetic annotation of tumors to improve cancer prevention, diagnosis, prognosis and therapy
    • Apply cutting-edge genetic technologies and bioinformatics and integrate genomic data sets with clinical and fundamental biological information
    • To characterize how the tumor microenvironment influences tumor cells and determines response to cancer therapies
  • Mohamed Lamkanfi Lab

    • ERC group
    • NOD-like receptor and inflammasome signaling networks,​ and their role in human disease
    • proteomics and genomics technologies for pathway discovery
  • Lennart Martens Lab

    • Data collection and integration across the various Omics fields
    • (Semi-)automatic quality control using configurable expert systems
    • Development of computational Omics
  • Stuart Maudsley Lab

    • Understanding complex and multifactorial neurodegenerative diseases by unraveling interaction networks of genes and proteins.
    • Generation of receptor-based therapeutic strategies to regulate pathological disease networks.
    • Development of novel bioinformatic tools for therapeutic design
  • Jan Michiels Lab

    • ​​Molecular and evolutionary aspects of persistence
    • Discovery of novel antibiotics
    • Engineering ethanol tolerance
  • Jeroen Raes Lab

    • ​novel computational approaches for large-scale, next-generation sequencing projects investigating the human microbiome
    • analysis of sequence data and the investigation of ecological communities from metagenomics, metatranscriptomics and meta-metabolomics
  • Yvan Saeys Lab

    • ​data mining and modeling for systems immunology
    • automation and design of novel computational tools to analyze data from high-throughput technologies
    • machine learning and automated reasoning for biomedical applications
  • Alan Urban Lab

    • ​Deciphering the neural circuits involved in local perfusion in normal and pathological brain
    • Recording and manipulating the dynamic patterns of neural/hemodynamic activities
    • Imaging animal behaviors
  • Yves Van de Peer Lab

    • ERC group
    • ​gene and genome annotation
    • comparative and evolutionary genomics
    • evolutionary systems biology
  • Kevin Verstrepen Lab

    • ERC group
    • Evolutionary mechanisms underlying hyper-evolvable properties
    • Yeast genetics and epigenetics
    • Importance of tandem repeats as drivers of genetic change