VIB scientists overview

Inflammation and immunity

  • Rudi Beyaert Lab

    • Protein-protein interactions, phosphorylation and ubiquitination
    • Cytokine, Toll-like receptor and T cell receptor signal transduction
    • NF-kappaB signaling in inflammation and cancer
    • Novel therapeutic targets and tools
  • Dirk Elewaut Lab

    • ​Mucosal inflammation and its link to joint disease
    • Immune regulation in health and arthritic disease with focus on iNKT cells and Tregs
    • Cellular stress and lipid homeostasis during autoimmune disease
    • Biomechanical stress in arthritis
    • Cartilage and bone homeostasis in steady state and in arthritic disease
  • Bart Lambrecht and Hamida Hammad Lab

    • ​Study of the molecular mechanism of DC-epithelial interaction in asthma and how this is influenced by infection and environment.
    • Study how the unfolded protein response interferes with the functioning of cells in the immune system and how this might lead to lung disease.
  • Markus Kleinewietfeld Lab

    • ​the immune cell balance as key regulator of human (auto)immune diseases
    • environmental factors in autoimmunity
    • plasticity of CD4+ T cells in health and disease
  • Bart Lambrecht and Hamida Hammad Lab

    • ​Study of the molecular mechanism of DC-epithelial interaction in asthma and how this is influenced by infection and environment.
    • Study how the unfolded protein response interferes with the functioning of cells in the immune system and how this might lead to lung disease.
  • Mohamed Lamkanfi Lab

    • NOD-like receptor and inflammasome signaling networks,​ and their role in human disease
    • proteomics and genomics technologies for pathway discovery
  • Claude Libert Lab

    • ​therapeutic potential of cytokines and their control mechanisms
    • matrix metalloproteinases (MMPs) and inflammation
    • determination of health status during aging
  • Adrian Liston Lab

    • understanding the human immune system in health and during disease
    • biology of regulatory T cells
    • mechanisms of diabetes and development of new models for screening anti-diabetic drugs
  • Xavier Saelens Lab

    • ​development of broad (universal) human influenza vaccines for both influenza A en B virus strains
  • Yvan Saeys Lab

    • ​data mining and modeling for systems immunology
    • automation and design of novel computational tools to analyze data from high-throughput technologies
    • machine learning and automated reasoning for biomedical applications
  • Savvas Savvides Lab

    • ​Pro-inflammatory signaling complexes mediated by TSLP
    • Extracellular signaling assemblies mediated by IL-12 family cytokines
    • Extracellular assembly and activation principles of oncogenic receptor tyrosine kinases
  • Jan Tavernier Lab

    • leptin receptors: molecular mechanisms underlying receptor activation upon ligand binding
    • MAPPIT two-hybrid toolbox based on JAK/STAT pathway
    • protein interactions important in the innate immune response
  • Jo Van Ginderachter Lab

    • ​myeloid cell heterogeneity and functions - functional genomics
    • Nanobodies against myeloid cell/inflammation markers
    • Tumor-host interactions
    • Trypanosome-host interactions
  • Geert van Loo Lab

    • NF-kB in inflammatory disease pathology
    • ER stress in inflammatory disease pathology
    • A20 in inflammation and autoimmune pathology
    • Development of new transgenic mouse models
  • Peter Vandenabeele Lab

    • cell death modalities in vivo
    • in vivo focus on epithelial biology: skin and intestine
    • transgenic mouse models for caspases and RIP kinases