VIB scientists overview

Cancer

  • Stein Aerts Lab

    • ​cellular decision making and genome regulation
    • single-cell transcriptomics and epigenomics
    • systems biology of gene regulation
    • gene regulatory networks in the Drosophila brain and retina
    • high-throughput enhancer assays and computational enhancer models
  • Gabriele Bergers Lab

    • Interaction of the tumor microenvironment and tumor cell compartment
    • Tumor niches and therapeutic resistance
    • Resistance to antiangiogenic therapy
    • Vascular and immunomodulation in cancer
  • Cédric Blanpain Lab*

    • ​embryonic development
    • stem cells and adult homeostasis
    • stem cells and tumor initiation
    • cancer stem cells
  • Peter Carmeliet Lab

    • ​Angiogenesis & Lymphangiogenesis
    • Neurobiology & Neurodegenration
    • Vessels, Oxygen & Metabolism
  • Jan Cools Lab

    • ​novel oncogenic mutations in leukemia
    • targeting deregulated pathways for leukemia therapy
    • cooperation of oncogenes during leukemogenesis
  • Sarah-Maria Fendt Lab

    • ​Cancer cells have a distinct metabolism adapted to their proliferative needs
    • Our focus is centered on understanding and targeting the differential metabolism of cancer cells
  • Georg Halder Lab

    • ​Novel signaling pathways in growth, regeneration and development in cancer
    • Translation of Drosophila knowledge to vertebrates
    • Mimic in-vivo by 2 and 3-dimensional hydrogel cultures
  • Diether Lambrechts Lab

    • connection between angiogenic factors and neurodegeneration
    • influence of SNPs, epigenetic changes and non-coding RNAs on gene expression and complex human traits and disease diversities
  • Claude Libert Lab

    • ​therapeutic potential of cytokines and their control mechanisms
    • matrix metalloproteinases (MMPs) and inflammation
    • determination of health status during aging
  • Massimiliano Mazzone Lab

    • genetic and molecular mechanisms regulating blood vessel endothelial cell fate
    • therapeutic angiogenesis for revascularization of ischemic tissues
  • Joris Messens Lab

    • Study of the proteins and mechanisms that control redox homeostasis
    • Biochemical, structural and quantum chemical expertise in thiol/redox-chemistry
  • Anna Sablina Lab

    • ​protein phosphatase complexes involved in control of cell transformation
    • models of cell transformation derived from manipulation of oncogenes and tumor suppressor genes
  • Massimo Santoro Lab

    • identify new metabolic pathways important in vascular development, homeostasis and disease
    • study redox signaling and antioxidant response in endothelial cells
  • Jo Van Ginderachter Lab

    • ​myeloid cell heterogeneity and functions - functional genomics
    • Nanobodies against myeloid cell/inflammation markers
    • Tumor-host interactions
    • Trypanosome-host interactions
  • Peter Vandenabeele Lab

    • cell death modalities in vivo
    • in vivo focus on epithelial biology: skin and intestine
    • transgenic mouse models for caspases and RIP kinases