VIB scientists overview

  • Stein Aerts Lab

    • ERC group​
    • cellular decision making and genome regulation
    • single-cell transcriptomics and epigenomics
    • systems biology of gene regulation
    • gene regulatory networks in the Drosophila brain and retina
    • high-throughput enhancer assays and computational enhancer models
  • Wim Annaert Lab

    • membrane transport in Alzheimer’s disease and congenital disorders of glycosylation type II​
    • ER-Golgi/endosomal trafficking - APP - gamma-secretase
  • Tom Beeckman Lab

    • formation of lateral-root primordia in the pericycle
    • involvement of cell-cycle regulation in the initiation of new organs
    • Auxin in the pericycle​
  • Gabriele Bergers Lab

    • Functional irregulation of the tumor microenvironment and tumor cell compartment
    • Tumor niches and therapeutic resistance
    • Resistance to antiangiogenic therapy
    • Vascular and immunomodulation in cancer
  • Rudi Beyaert Lab

    • Protein-protein interactions, phosphorylation and ubiquitination
    • Cytokine, Toll-like receptor and T cell receptor signal transduction
    • NF-kappaB signaling in inflammation and cancer
    • Novel therapeutic targets and tools
  • Cédric Blanpain Lab*

    • ​embryonic development
    • stem cells and adult homeostasis
    • stem cells and tumor initiation
    • cancer stem cells
  • Wout Boerjan Lab

    • bio-energy research on poplar and Arabidopsis 
    • biosynthesis, polymerization and structure of lignin
  • Vincent Bonin Lab

    • visual processing in the mammalian brain
    • ​network dynamics and computations
    • neural circuits and behavior
  • Nico Callewaert Lab

    • ERC group
    • ​Synthetic biology of the eukaryotic secretory system
    • Novel concepts in biopharmaceuticals
    • Novel technology for discovery of molecular biomarkers of disease
    • Engineering the Mycobacterium-host interface for better vaccines and drugs
  • Bruno Cammue Lab*

    • antimicrobial plant peptides including plant defensins
    • novel stress-induced plant peptides
    • plant-fungus interactions and plant disease analysis
    • biocontrol of plant diseases
  • Peter Carmeliet Lab

    • ERC group​
    • Vascular metabolism & (lymph)angiogenesis
    • Omics analysis of healthy and diseased human and mouse endothelial/vascular cells to understand and target metabolic pathways
    • Therapeutic anti-angiogenesis: tumor vessel normalization (TVN)
    • Endothelial cell metabolic target discovery and drug development
  • Lucía Chávez-Gutiérrez Lab

    • ​​Intramembrane proteolytic mechanism
    • Quantitative enzymology
    • Structure and function of proteases in neurodegeneration
  • Jan Cools Lab

    • ERC group
    • ​novel oncogenic mutations in leukemia
    • targeting deregulated pathways for leukemia therapy
    • cooperation of oncogenes during leukemogenesis
  • Geert De Jaeger Lab

    • develop interactomic technology to study gene and protein networks regulating plant growth
    • use network knowledge to discover new approaches for the engineering of plant growth
  • Peter De Jonghe Lab

    • ​peripheral neuropathies, epilepsy 
    • progressive external ophthalmoplegia, spastic paraplegias
    • gene mapping and cloning
  • Bert De Rybel Lab

    • ERC group​
    • the Plant Vascular System
    • Unraveling molecular mechanisms controlling development
    • Oriented cell divisions
    • Control in space and time generate a functional 3D organ
  • Ive De Smet Lab

    • ​unraveling phosphorylation-related signaling mechanisms associated with cell division and differentiation in plants
  • Bart De Strooper Lab

    • ERC group​
    • Basic mechanisms of Alzheimer’s and Parkinson’s disease
    • Secretases of the amyloid peptide
    • Intramembrane proteolysis as a signaling mechanism
  • Lieven De Veylder Lab

    • mechanisms that control the timing of cell cycle exit
    • cell cycle adjustment by DNA stress checkpoint mechanisms
  • Joris de Wit Lab

    • ERC group
    • ​molecular mechanisms of neuronal connectivity
    • role of cell adhesion molecules in synapse development and function
  • Ann Depicker Lab

    • ​agrobacterium-mediated transformation: T-DNA integration
    • RNA silencing in plants
    • molecular farming
  • Rouslan Efremov Lab

    • ​Structure and conformational dynamics of membrane protein complexes by cryo-EM
    • Single particle cryo-EM method development
  • Dirk Elewaut Lab

    • ​Mucosal inflammation and its link to joint disease
    • Immune regulation in health and arthritic disease with focus on iNKT cells and Tregs
    • Cellular stress and lipid homeostasis during autoimmune disease
    • Biomechanical stress in arthritis
    • Cartilage and bone homeostasis in steady state and in arthritic disease
  • Sven Eyckerman Lab

    • ​protein complex biology
    • Virotrap: purification of protein complexes using virus-like particles
    • genome engineering to support interactomics
    • multiplex profiling in signal pathways
  • Sarah-Maria Fendt Lab

    • ​Cancer cells have a distinct metabolism adapted to their proliferative needs
    • Our focus is centered on understanding and targeting the differential metabolism of cancer cells
  • Bioinformatics Service Lab

    • ​​data analysis and interpretation of sequence data 
    • spatial and  single-cell transcriptomics
    • genomics - transcriptomics
  • Holger Gerhardt Lab

    • ERC group
    • Importance of tip cell biology in vascular patterning, tumour angiogenesis and ischemic disease

     

  • Kris Gevaert Lab

    • Contemporary mass spectrometry-driven proteomics
    • Protein modifications
    • Proteogenomics
  • Michele Giugliano Lab

    • Biophysics of computations in single neurons
    • Experimental investigations of dynamical response properties of cortical neurons
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