VIB scientists overview

  • Stein Aerts Lab

    • ERC group​
    • cellular decision making and genome regulation
    • single-cell transcriptomics and epigenomics
    • systems biology of gene regulation
    • gene regulatory networks in the Drosophila brain and retina
    • high-throughput enhancer assays and computational enhancer models
  • Patrizia Agostinis Lab

    ​“We are studying cell death and resistance pathways in tumors, how they impact the interface between cancer cells and stromal cells, modify the tumor microenvironment and anticancer therapy responses. Our ultimate goal is to contribute to combating cancer by translating molecular/cellular knowledge into therapeutic possibilities”​
  • Wim Annaert Lab

    • membrane transport in Alzheimer’s disease and congenital disorders of glycosylation type II​
    • ER-Golgi/endosomal trafficking - APP - gamma-secretase
  • Tom Beeckman Lab

    • formation of lateral-root primordia in the pericycle
    • involvement of cell-cycle regulation in the initiation of new organs
    • Auxin in the pericycle​
  • Gabriele Bergers Lab

    • Functional irregulation of the tumor microenvironment and tumor cell compartment
    • Tumor niches and therapeutic resistance
    • Resistance to antiangiogenic therapy
    • Vascular and immunomodulation in cancer
  • Rudi Beyaert Lab

    • Protein-protein interactions, phosphorylation and ubiquitination
    • Cytokine, Toll-like receptor and T cell receptor signal transduction
    • NF-kappaB signaling in inflammation and cancer
    • Novel therapeutic targets and tools
  • Cédric Blanpain Lab*

    • ​ERC group
    • embryonic development
    • stem cells and adult homeostasis
    • stem cells and tumor initiation
    • cancer stem cells
  • Wout Boerjan Lab

    • bio-energy research on poplar and Arabidopsis 
    • biosynthesis, polymerization and structure of lignin
  • Vincent Bonin Lab

    • visual processing in the mammalian brain
    • ​network dynamics and computations
    • neural circuits and behavior
  • Nico Callewaert Lab

    • ERC group
    • ​Synthetic biology of the eukaryotic secretory system
    • Novel concepts in biopharmaceuticals
    • Novel technology for discovery of molecular biomarkers of disease
    • Engineering the Mycobacterium-host interface for better vaccines and drugs
  • Bruno Cammue Lab*

    • antimicrobial plant peptides including plant defensins
    • novel stress-induced plant peptides
    • plant-fungus interactions and plant disease analysis
    • biocontrol of plant diseases
  • Peter Carmeliet Lab

    • ERC group​
    • Vascular metabolism & (lymph)angiogenesis
    • Omics analysis of healthy and diseased human and mouse endothelial/vascular cells to understand and target metabolic pathways
    • Therapeutic anti-angiogenesis: tumor vessel normalization (TVN)
    • Endothelial cell metabolic target discovery and drug development
  • Lucía Chávez-Gutiérrez Lab

    • ​​Intramembrane proteolytic mechanism
    • Quantitative enzymology
    • Structure and function of proteases in neurodegeneration
  • Jan Cools Lab

    • ERC group
    • ​novel oncogenic mutations in leukemia
    • targeting deregulated pathways for leukemia therapy
    • cooperation of oncogenes during leukemogenesis
  • Karolien De Bosscher Lab

    • Nuclear Receptors - Understand how these transcription factors interact and crosstalk at the genome-wide level
    • ​Glucocorticoid Receptor – Develop drug discovery platforms
     
  • Geert De Jaeger Lab

    • develop interactomic technology to study gene and protein networks regulating plant growth
    • use network knowledge to discover new approaches for the engineering of plant growth
  • Bert De Rybel Lab

    • ERC group​
    • the Plant Vascular System
    • Unraveling molecular mechanisms controlling development
    • Oriented cell divisions
    • Control in space and time generate a functional 3D organ
  • Ive De Smet Lab

    • ​unraveling phosphorylation-related signaling mechanisms associated with cell division and differentiation in plants
  • Bart De Strooper Lab

    • Basic mechanisms of Alzheimer’s and Parkinson’s disease
    • Secretases of the amyloid peptide
    • Intramembrane proteolysis as a signaling mechanism
  • Lieven De Veylder Lab

    • mechanisms that control the timing of cell cycle exit
    • cell cycle adjustment by DNA stress checkpoint mechanisms
  • Joris de Wit Lab

    • ERC group
    • ​molecular mechanisms of neuronal connectivity
    • role of cell adhesion molecules in synapse development and function
  • Rouslan Efremov Lab

    • ERC group
    • Structure and conformational dynamics of membrane protein complexes by cryo-EM
    • Single particle cryo-EM method development
  • Dirk Elewaut Lab

    • ​Mucosal inflammation and its link to joint disease
    • Immune regulation in health and arthritic disease with focus on iNKT cells and Tregs
    • Cellular stress and lipid homeostasis during autoimmune disease
    • Biomechanical stress in arthritis
    • Cartilage and bone homeostasis in steady state and in arthritic disease
  • Sven Eyckerman Lab

    • ​protein complex biology
    • Virotrap: purification of protein complexes using virus-like particles
    • genome engineering to support interactomics
    • multiplex profiling in signal pathways
  • Sarah-Maria Fendt Lab

    • ERC group
    • Cancer cells have a distinct metabolism adapted to their proliferative needs
    • Our focus is centered on understanding and targeting the differential metabolism of cancer cells
  • Holger Gerhardt Lab

    • ERC group
    • Importance of tip cell biology in vascular patterning, tumour angiogenesis and ischemic disease

     

  • Metabolomics Expertise Center

    • ​metabolism: (un)targeted profiling of diverse classes of metabolites
    • mass spectrometry: gas and liquid chromatography set-ups
    • metabolic crosstalk: epigenetics, protein modifications, ....
    • 13C metabolic tracer studies
  • Rose Goodchild Lab

    • ​Molecular and cellular pathology of hereditary dystonias
    • Dystonia proteins in neurodevelopment
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