Research focus

The DMBR microscopy core is a resource center for advanced light, laser and electron microscopy, providing investigators with consultation and training on proper use of suitable microscopes and related instruments, sample preparation, and dye and reagent selection. The facility was established in 2003 by combining all the microscopy resources and associated equipment of the DMBR, and optimizing their location in the new research building at the Technology Park. In 2004, the Core was expanded with advanced multidimensional live cell imaging facilities and immunoelectron microscopy technology. Other routine tasks include: confocal laser scanning microscopy, advanced digital fluorescent imaging, and use of various types of inverted microscopes for the observation of tissue cultures and model organisms under contrasted brightfield or fluorescent illumination conditions.

All instrumentation is either available directly to investigators with appropriate training, or with core support. Imaging services include digital imaging, processing and analysis on a workstation networked with a photo-quality printer. Data, images and reports are stored on an appropriate intranet storage device maintained by the IT core.

The facility also aims to train members of the research staff who require these microscopes as an everyday tool in their research. Furthermore, classes are offered regularly as periodic workshops, on topics that include advanced immunocytochemistry and digital image processing and analysis. Training can also be customized for groups and individuals, and may include both standard procedures and specialized applications for specific research projects and protocol development.
The core is supported by the DMBR, and priority is given to departmental members; collaborations with outside laboratories are considered on the basis of availability.