VIB-KU Leuven Center for Brain & Disease Research

Science Director: Patrik Verstreken

Our center's mission is to perform frontline research, addressing significant questions and key issues relevant to major human health challenges. We focus on basic molecular and cellular mechanisms and use the power of modern genetics and genomics as well as molecular, cellular and developmental biology. The center fosters and promotes excellence in research, with a strong trust in both the creativity of individual researchers and the benefit of synergistic interactions. The center aims to be an internationally visible center of excellence, providing knowledge, expertise and training to the scientific community, students and medical industry. 

Patrik Verstreken explains his strategy

VIB-KU Leuven Center for Brain & Disease Research

Scientists & research:

  • Stein Aerts Lab
    Drosophila neurogenomics - cis-regulatory code - gene regulatory networks - single-cell transcriptomics - epigenomic landscapes
  • Wim Annaert Lab
    Alzheimer’s disease - congenital disorders of glycosylation - ER-Golgi/endosomal trafficking - APP - gamma-secretase
  • Lucía Chávez-Gutiérrez Lab
    intramembrane proteolysis - presenilin - APP - Alzheimer's disease - nanobodies
  • Sandrine Da Cruz Lab
    amyotrophic lateral sclerosis (ALS); frontotemporal dementia (FTD); neurodegeneration; motor neurons; neuromuscular diseases; mouse models; induced pluripotent stem cells (iPSCs)
  • Bart De Strooper Lab
    Alzheimer’s disease - proteolytic enzymes and secretases - APP and presenilin - miRNA-intramembrane proteolysis - Parkinson disease
  • Joris de Wit Lab
    synapse - connectivity - circuit - cell adhesion - cognition
  • Matthew Holt Lab
    Astrocyte - Neuron-Astrocyte Interactions - Neurophysiology-Neuropathology
  • Lynette Lim Lab
    Neuronal development; neural circuits; cortical interneurons
  • Adrian Liston Lab
    immunology - genomics - autoimmunity - regulatory T-cells - diabetes
  • Sha Liu Lab
    sleep - synaptic plasticity - learning and memory - neural circuit - glia
  • Light Microscopy Lab
    imaging - microscopy - super-resolution - cell membrane molecule distribution
  • Electron Microscopy Lab
    Electron microscopy - plasticity - connections - synapses
  • Frederic Rousseau and Joost Schymkowitz Lab
    protein aggregation - protein stability - protein design - protein interaction - force field - Alzheimer beta-peptide
  • Dietmar Schmucker Lab
    Drosophila - Xenopus tropicalis - neuronal wiring - growth cone signaling - axon branching - dendrite morphogenesis - central nervous system - regenerative medicine - innate immunity
  • Bioinformatics Service Lab
    sequencing - single-cell - genomics - transcriptomics - regulation
  • Ludo Van Den Bosch Lab
    amyotrophic lateral sclerosis - stroke - motor neuron - neurodegeneration - animal models - iPSC
  • Pierre Vanderhaeghen Lab
    brain development, neurogenesis, pluripotent stem cells, brain evolution
  • Patrik Verstreken Lab
    synapse - neurotransmitter release and endocytosis - Drosophila - mitochondria - imaging and electrophysiology
  • Thomas Voets Lab
    ion channels - electrophysiology - sensory systems - pain - thermosensation


VIB-KU Leuven Center for Brain & Disease Research
O&N 4, 6e verd Campus GasthuisbergHerestraat 49, bus 602  3000 LEUVEN BELGIUM
+32 16 37 31 02
+32 16 37 27 00
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Hosting: VIB Bioimaging Core

The VIB Bioimaging Core has specialist instrumentation for both light and electron microscopy and are developing Correlative Light and Electron Microscopy (CLEM) approaches to answer complex biological questions. The cores have a diverse instrument base providing the most suitable instrumentation for any imaging need.

The VIB Bioimaging Core is a dual site facility with platforms in Ghent and Leuven and serves both academic and industrial life sciences community. The center for Brain & disease research is hosting the Leuven site. For more information:

VIB Bioimaging Core

Hosting: VIB Flow Core

The VIB Flow Core provides access to high quality flow cytometry and fluorescence-activated cell sorting (FACS). The Core aims to provide highly trained staff and the most modern equipment to all prospective users, in order to facilitate elite research through the use of flow cytometry. Flow Core staff operate and maintain the analytical cytometers and cell sorters, assist researchers in protocol selection and development, train students, post-doctoral fellows and technologists how to operate the analytical cytometers and provide support in data analysis software. The facility also organizes quarterly workshops and seminars to provide continuing education opportunities and to keep users abreast of developing technologies.