Department Director: Bart De Strooper
Our department's mission is to perform frontline research, addressing significant questions and key issues relevant to major human health challenges. We focus on basic molecular and cellular mechanisms and use the power of modern genetics and genomics as well as molecular, cellular and developmental biology. The department fosters and promotes excellence in research, with a strong trust in both the creativity of individual researchers and the benefit of synergistic interactions. The department aims to be an internationally visible centre of excellence, providing knowledge, expertise and training to the scientific community, students and medical industry.
VIB Center for the Biology of Disease, KU Leuven
Department Director: Prof. Dr. Bart De Strooper
Scientists & research:
- Wim Annaert Lab
Alzheimer’s disease - congenital disorders of glycosylation - ER-Golgi/endosomal trafficking - APP - gamma-secretase - Claudia Bagni Lab
mRNA localization - local protein synthesis - synaptic plasticity - spine dysmorphogenesis - fragile X Syndrome - Patrick Callaerts Lab
Drosophila - behavior - development - genetics - aggression - Jan Cools Lab
leukemia - oncogene - tyrosine kinase - therapy - drug screen - Guido David Lab
heparan sulfate proteoglycans - syndecan - glypican - heparanase - vesicular trafficking - morphogen-signaling - Bart De Strooper Lab
Alzheimer’s disease - proteolytic enzymes and secretases - APP and presenilin - miRNA-intramembrane proteolysis - Parkinson disease - Joris de Wit Lab
synapse, connectivity, circuit, cell adhesion, cognition - Carlos Dotti Lab
neuron - hippocampus - aging - Drosophila - membrane - gene and drug screening - Rose Goodchild Lab
dystonia, neurological disease, cell biology, nuclear envelope, sarcoglycan - Georg Halder Lab
signaling pathway - cancer - Drosophila - 3-dimension - Bassem Hassan Lab
brain - neural circuit - genetics - Drosophila - neuronal cell biology - Matthew Holt Lab
Astrocyte - Neuron-Astrocyte Interactions - Neurophysiology-Neuropathology - Jean-Christophe Marine Lab
molecular oncology - p53 - gene silencing (knock-out and knock-in) - retroviral gene transfer - Anna Sablina Lab
human cell transformation - functional genomics - cell signaling - protein phosphatase - Patrik Verstreken Lab
synapse - neurotransmitter release and endocytosis - Drosophila - mitochondria - imaging and electrophysiology - An Zwijsen Lab
mouse embryo - stem cell - amnion - cardiovascular development -TGF/Smad
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