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Important role of nucleocytoplasmic transport in amyotrophic lateral sclerosis and frontotemporal dementia
12 February 2016
Moreover, these insights have a solid basis, since they come from 4 different scientific angles. It is an important next step in our understanding of these terrible diseases.”
Neurogenesis - Discovery of a new regulatory mechanism
28 January 2016
A mechanism, found by Bassem Hassan's team, is a simple reversible chemical modification, critical for the production of sufficient number of neurons, their differentiation and the development of the nervous system.
VIB researchers discover possible strategy against stroke
7 January 2016
Research led by prof. Peter Carmeliet and dr. Annelies Quaegebeur (VIB/KU Leuven) indicates that inhibition of PHD1 offers protection against stroke, via an unexpected mechanism, raising hope for future stroke treatment.
VIB research presents new insights in the search for treatments for neurological diseases
18 November 2015
A team of researchers led by professor Patrik Verstreken (VIB/KU Leuven) has exposed the fine details of a mechanism that provides more insight in the communication between neurons.
Breakthrough research reveals a new target for Alzheimer's disease treatment
14 October 2015
A research team led by Amantha Thathiah (VIB/KU Leuven) has determined that a protein – known as GPR3 – might play an important role in alleviating the cognitive deficits and reducing the generation of ‘amyloid plaques’.
Disruption of brain-blood barrier might influence progression of Alzheimer’s
29 September 2015
The team of Roosmarijn Vandenbroucke in the Claude Libert Group (VIB/UGent) combined their knowledge and expertise related to inflammation with the expertise in Alzheimer’s disease present in the Bart De Strooper Group (VIB/KU Leuven).
Alzheimer’s-disease-related proteases, BACE1 and APH1B-y-secretase, control axonal guidance by regulating growth cone dynamics
14 September 2015
BACE1 is the major drug target for Alzheimer’s disease. Soraia Barão and Bart De Strooper (VIB/KU Leuven) now show that this protease is critically involved in axonal guidance processes in thalamic and hippocampal neurons.
New insights in pathological mechanism that causes dysfunctional synapses
20 August 2015
Genetic analysis of human patients has shown that mutations in genes involved in synaptic communication can drive neuropsychiatric and neurological diseases such as autism spectrum disorder and Alzheimer’s disease.
Polyglutamine repeats play key role in functional development of cells
11 August 2015
Scientists at VIB and KU Leuven have revealed that variable polyglutamine repeats in the DNA tune the function of the protein in which they reside. To date, these repeats were known only to cause severe neurodegenerative diseases such as Huntington’s.
Potential target pathway may pave the way for new therapeutic approaches for fragile X syndrome and autism
16 July 2015
The discovery that it might also contribute to FXS, a neurodevelopmental disorder occurring at a young age, is remarkable.
549,490 Euros from Stichting Alzheimer Onderzoek (Alzheimer’s Research Foundation) for 6 VIB researchers
3 July 2015
In 2014, Stichting Alzheimer Onderzoek (SAO) awarded a total of 991,390 Euros in funding (2015 - 2016) to 12 research projects.
New insights could result in changes to the therapeutic strategy to combat Alzheimer’s
26 May 2015
Scientists at VIB, KU Leuven and Janssen Pharmaceutica have demonstrated that the distribution of aggregates through the brain is facilitated by synaptic connections between brain cells.
Stem cell research offers new insights into how dementia develops
5 January 2015
Researchers at KU Leuven and the Vlaams Instituut voor Biotechnologie (VIB) have succeeded in correcting a genetic mutation thought to cause frontotemporal dementia.
Has a possible new lead been found in the fight against neurodegenerative diseases?
24 November 2014
Researchers from VIB and KU Leuven have succeeded in completely suppressing neurodegeneration in fruit flies, by partially inhibiting the breakdown of 'defective' proteins in brain cells.
Top Talk Peter Carmeliet 'Breaking Boundaries'
18 November 2014
On Tuesday November 18, Peter Carmeliet (VIB Vesalius Research Center, KU Leuven) took his audience on an exploration of the world of blood vessels.
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