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Postdoctoral Scientist
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VIB group
Department of Molecular and Developmental Genetics
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Job description
Parkinson’s disease (PD) is the second most common neurodegenerative disease and causative mutations in different genes have been identified, allowing us to model PD in genetic model organisms. Several PD related genes have been linked to synaptic function and we are using flies and mice to study the molecular aspects of neuronal communication in PD models. Hence, our studies will help elucidate pathological but also normal brain function with the ultimate hope to use this knowledge for therapeutic purposes.
You will use novel genetic screening strategies to identify genetic factors that modulate PD-related phenotypes in flies. By combining in vivo assays such as electrophysiology and live imaging with cellular and molecular techniques, you will be responsible for the characterization of these novel genes.
We offer a 2 year contract and a competitive salary.
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Profile
Given that this project is part of a large research effort to understand PD at the interface of the De Strooper and Verstreken labs, you must be a real team-player. In addition, expert skills in molecular biology, protein chemistry and/or microscopy are essential, while proficiency in Drosophila genetics, electrophysiological analyses and/or cell culture are/is a definite plus.
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Contact
If you are interested in studying the mechanisms of neuronal communication, and you are a motivated and interactive individual, please send your CV, a short letter of motivation and the names of 3 referees to Patrik Verstreken - address department |
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