Pierre Hilson
Functional Genomics
VIB Department of Plant Systems Biology, UGent

PhD: Gembloux Agricultural Univ., Gembloux, Belgium, '91 VIB Group leader since 2002 VIB Division Coordinator since 2002

e-mail phone +32 9 331 38 30 ADDRESS

Current team members
Group leader: Pierre Hilson
Staff scientist: Mansour Karimi-Dehkordi
Postdoctoral scientists: Chiara Consonni, Guillaume Queval
Ph.D. Students: Ana Fernandez Salina, Sarieh Ghorbani
Support personnel: Andrzej Drozdzecki, Björn De Meyer, Nino Villarroel, Rebecca De Clercq, Rudy Vanderhaeghen, Wilson Ardiles Diaz

Keywords
hairpin RNA silencing - RNA interference -ORFeome - promoterome - Gateway recombinational cloning

Science

The Arabidopsis genome sequence offers an extremely important resource for researchers involved in comparative genomics. Today however, we have some experimental proof of function for less than 20% of its 23,000 genes. Large-scale methods for determining gene function are therefore crucial for rapid progress. The overall goal of the functional genomics division is to forge and exploit novel tools to conduct genome-scale functional analyses of plant genes, taking advantage of all sequence information available.
  
The following projects are conducted in the functional genomics group:
· Creation of sequence repertoires for Arabidopsis functional analyses at the genome scale
· Hairpin RNA silencing of Arabidopsis genes
· Mapping of gene transcriptional activity in plant tissues
. Automation of plant cell transformation
. Macroscopic and microscopic cell assays
. Vector development

Related websites:
www.agrikola.org
www.catma.org
www.orfeome.org
www.psb.ugent.be/gateway
www.psb.ugent.be/SAP

Benhamed M, Martin-Magniette M, Taconnat L, Bitton F, Servet C, De Clercq R, De Meyer B, Buysschaert C, Rombauts S, Villarroel R, Aubourg S, Beynon J, Bhalerao R, Coupland G, Gruissem W, Menke F, Weisshaar B, Renou J, Zhou D, Hilson P
Genome-scale Arabidopsis promoter array identifies targets of the histone acetyltransferase GCN5
PLANT J 56, 493-504, 2008



Whitford R, Fernandez Salina A, De Groodt R, Ortega E, Hilson P
Plant CLE peptides from two distinct functional classes synergistically induce division of vascular cells
P NATL ACAD SCI USA 105, 18625-30, 2008



Karimi M, Bleys A, Vanderhaeghen R, Hilson P
Building blocks for plant gene assembly
PLANT PHYSIOL 145, 1183-91, 2007



Hilson P
Cloned sequence repertoires for small- and large-scale biology
TRENDS PLANT SCI 11, 133-41, 2006



Hilson P, Allemeersch J, Altmann T, Aubourg S, Avon A, Beynon J, Bhalerao p, Bitton F, Caboche M, Cannoot B, Chardakov V, Cognet-Holliger C, Colot V, Crowe M, Darimont C, Durinck S, Eickhoff H, Falcon De Longuevialle A, Farmer e, Grant M, Kuiper M, Lehrach H, Léon C, Leyva A, Lundeberg J, Lurin C, Moreau Y, Nietfeld W, Paz-Ares J, Reymond P, Rouzé P, Sandberg G, Segura D, Serizet C, Tabrett A, Taconnat L, Thareau V, Van Hummelen P, Vercruysse S, Vuylsteke M
Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications
GENOME RES 14, 2176-2189, 2004

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