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Mieke Van Lijsebettens
Chromatin and Growth Control
VIB Department of Plant Systems Biology, UGent
PhD: Univ. of Ghent, Ghent, Belgium, '84
Principal Investigator VIB since 1998 |
e-mail
phone +32 9 331 39 70
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Current team members
Group leader: Mieke Van Lijsebettens
Postdoctoral scientists: Basel Khraiwesh, Kristiina Himanen
Ph.D. Student: Steven De Groeve
Support personnel: Carina Braeckman, Griet Coussens, Pia Neyt, Stijn Aesaert
Keywords
biomass production - leaf formations - chromatin - growth control - forward and reverse genetics
Science
Leaf growth is the basis for biomass and yield. Insight into the molecular mechanisms that direct leaf size, shape and number will result in genetic tools to improve food and bio-energy production. Development of leaves is genetically determined as shown by species-specific size and shape; in addition plasticity in leaf formation is induced by a number of environmental factors such as day length, water deficit and light quality. The aim of the research unit “Chromatin and Growth Control”, headed by Mieke Van Lijsebettens, is to identify genetic and epigenetic control mechanisms that determine leaf growth, to position these in molecular networks consisting of upstream signaling pathways linked to environment and downstream target genes, in the model plant Arabidopsis thaliana. Methodologies used are forward and reverse genetics, morphological, cytological and molecular phenotyping, interactome construction of complexes, gene expression analyses in relation to chromatin modifications. Maize is used for translational research.
Selected Publications
Robles P, Fleury D, Candela H, Cnops G, Alonso-Peral M, Anami S, Falcone A, Caldana C, Willmitzer L, Ponce M, Van Lijsebettens M, Micol J
The RON1/FRY1/SAL1 gene is required for leaf morphogenesis and venation patterning in Arabidopsis
PLANT PHYSIOL e-pub, e-pub, 2010
Nelissen H, De Groeve S, Fleury D, Neyt P, Bruno L, Bitonti M, Vandenbussche F, Van Der Straeten D, Yamaguchi T, Tsukaya H, Witters E, De Jaeger G, Houben A, Van Lijsebettens M
Plant Elongator regulates auxin-related genes during RNA polymerase II transcription elongation
P NATL ACAD SCI USA e-pub, e-pub, 2010
Lolas I, Himanen K, Gronlund J, Lynggaard C, Houben A, Melzer M, Van Lijsebettens M, Grasser K
The transcript elongation factor FACT affects Arabidopsis vegetative and reproductive development and genetically interacts with HUB1/2
PLANT J e-pub, e-pub, 2010
Fleury D, Himanen K, Cnops G, Nelissen H, Boccardi T, Maere S, Beemster G, Neyt P, Anami S, Robles P, Micol J, Inzé D, Van Lijsebettens M
The Arabidopsis thaliana homolog of yeast BRE1 has a function in cell cycle regulation during early leaf and root growth
PLANT CELL 19, 417-32, 2007
Cnops G, Neyt P, Raes J, Petrarulo M, Nelissen H, Malenica N, Luschnig C, Tietz O, Ditengou F, Palme K, Azmi A, Prinsen E, Van Lijsebettens M
The TORNADO1 and TORNADO2 genes function in several patterning processes during early leaf development in Arabidopsis thaliana
PLANT CELL 18, 852-66, 2006
Search Publications
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